Earlier, it has also been demonstrated that Garcinol, a dietary molecule, synergizes with gemcitabine to inhibit cell proliferation and induces apoptosis in MIA PaCa-2 cells with significant modulation of key cancer regulators, including PARP, VEGF, MMPs, ILs, caspases, and NF-κB [41]. Here, NFKB1 is linked to cancer.