On the other hand, inhibition of sorcin expression by sorcin-targeting RNA interference led to reversal of drug resistance in the following cell lines: MDR K562/A02 and sorcin-transfected K562; MCF-7/A02; HeLa; colorectal cancer; and CNE2/DDPls [37,38,39,40,41,42,43]. Here, SRI is linked to colorectal cancer.