A candidate gene in this region is Slc11a1 (solute carrier family 11; proton-coupled divalent metal ion transporters, member 1 (formerly known as Nramp1)) which is a major gene regulating control of intracellular pathogen infections such as those caused by Salmonella Typhimurium, Leishmania donovani, and Mycobacterium bovis bacillus Calmette-Guerin (BCG) in mice and humans. The gene discussed is SLC11A1; the disease is infection.