Intratracheal transfer to wild-type mice of OVA-primed bone marrow-derived DCs from OGR1-deficient mice developed lower AHR and eosinophilia as compared with the transfer of those from wild-type mice, which was associated with lower migratory activity to the peribronchial lymph nodes in OGR1-deficient DCs than in wild-type DCs. The gene discussed is AHR; the disease is Increased total eosinophil count.