The local production and secretion of HIV/SIV-specific secretory IgA and transudated IgG might also prevent mucosal cell infection and/or help control viral dissemination by virus entrapment and immune exclusion [11] or by other as yet unidentified mechanisms or functional activities such as neutralization and inhibition of transcytosis across the mucosal barrier [12,13,14,15,16,17]. This evidence concerns the gene CD79A and infection.