Thus far, congenital cataracts have been associated with the following genes: 10 crystallin genes (CRYAA, CRYAB, CRYBB1, CRYBB2, CRYBA1/A3, CRYGA, CRYGB, CRYGC, CRYGD, CRYGS) [1–4], 3 membrane protein genes (GJA3, GJA8 and MIP) [5–7], beaded filament structural protein-2 (BFSP2) [8], a ferritin light chain gene (TFL) [9], transcription regulatory factors genes (MAF, PITX3, HSF4, PAX6) [10–12], connexin 46 (Cx46) [13], aspartate-47 of the Connexin50 gene (Cx50D47) [14], a receptor tyrosine kinase gene (EPHA2) [15], and the Wolfram gene (WFS1) [16]. This evidence concerns the gene GJA3 and early-onset non-syndromic cataract.