AKT1 and neoplasm: The Src/FAK pathway kinases are core components of signaling initiated by growth factors, integrins and cytokine receptors to activate downstream signaling cascades such as Ras/Raf/MAPK, PI3K/AKT and STATs [27, 33-35] that control tumor growth [36] and other cellular process such as cell motility, adhesion [27] and EMT [37].