Although the remaining 7 genes (PKD1, FAM38A, WDR81, TMEM136, SLC36A1, SLC26A6, IGFLR1) are mutated in >10% of the colorectal cancer cell lines, literature searches did not reveal evidence of the functional role or therapeutic potential of these genes in colorectal cancer. The gene discussed is PKD1; the disease is colorectal cancer.