ICAM1 and Hyperglycemia: A 16.5-mM glucose concentration not only is known to simulate a diabetic state but also is associated with hyperglycemia-mediated vascular inflammation through increased expression of endothelial adhesion molecules, such as endothelial-leukocyte adhesion molecule 1 (ELAM-1), vascular cell adhesion molecule-1 (VCAM-1), and intercellular adhesion molecule-1 (ICAM-1) (Takami et al. 1998; Altannavch et al. 2004).