Although we could not rule out the possibility of Th17 cytokine-producing cells other than those described here, NKp46+ cells, LTi-like cells, γδT cells and CD11c+ cells were thought to be rapid innate sources of IL-22, which is required in the early stage to maintain epithelial cell integrity and to suppress eosinophilia. This evidence concerns the gene IL22 and Increased total eosinophil count.