CYCS and hepatocellular carcinoma: Their mode of action concentrates on induction of mitochondrial apoptotic pathway, e.g., mitochondria depolymerization, cytochrome c release and activation of caspases, in various cancer cell lines, including prostate cancer [20], nasopharyngeal carcinoma [21], melanoma [22], breast cancer [23], pancreatic cancer [24,25], gastric cancer [26], cervical cancer [27,28] and hepatoma cells [29].