Treatment with CGA (400 mg/kg) or atorvastatin (4 mg/kg) for 12 weeks significantly reduced vascular wall thickness of the ascending aorta 2 cm above the aortic valve (AV, arrow) and at the origin of the brachiocephalic (BC) artery (Figure 2), suggesting that CGA inhibits aortic dilatation in ApoE−/− mice. Here, APOE is linked to Vascular dilatation.