In addition to adding both IFN to macrophages at the time of infection, we also repeated the experiment with 2 h of IFN-β pretreatment, prior to infection and IFN-γ addition, or 2 h of IFN-γ pretreatment, followed by infection and IFN-β addition, and we found the same results in both cases as adding both IFN at the time of infection that type I IFN effects are dominant (data not shown). This evidence concerns the gene IFNB1 and infection.