ACP5 and Peri-Implantitis: A differentiation of peri-implantitis to other inflammatory periodontal processes cannot be made on the basis of human saliva by markers such as osteocalcin, tartrate-resistant acid phosphatase (TRAP), dickkopf-related protein-1 (DKK-1), osteoprotegerin (OPG) and cathepsin K (CatK) [9,14].