13 Milanski Milanski M M Degasperi Degasperi G G Coope Coope A A Morari Morari J J Denis Denis R R Cintra Cintra DE DE et al. et al. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity. This evidence concerns the gene TLR4 and obesity disorder.