Before assessing the effects of LXR ligands in PDAC cells, we first demonstrated that LXRβ is the main LXR isoform expressed in human pancreatic ductal epithelial cells, as LXRα is not detectable in human normal pancreatic ducts (figure 1E), pancreatic adenocarcinoma (Figure 1F), or in PDAC cell lines (Figure 1H). This evidence concerns the gene NR1H3 and pancreatic adenocarcinoma.