For example, Suzuki et al reported that the combination of a baseline and rate of change of serum ALT and AST levels had an AUROC of 0.72 and 0.73, respectively, in predicting improvement, and an AUROC of 0.75 and 0.77, respectively, in predicting worsening of histological inflammation in NASH subjects. Here, GPT is linked to metabolic dysfunction-associated steatohepatitis.