There was a trend to higher levels of activated JNK (p54; P-T183/Y185) and MST1 (P-T183) in the cortical region of scrapie-infected mice at 70 dpi (two-tail paired ratio t-test; JNK [p54], P = 0.0851; MST1, P = 0.0880) (Figure 8). The gene discussed is MAPK8; the disease is scrapie.