Table 1 shows our estimations of ischemia onset time, i.e., estimated PIO times, calculated from the decreases of NAA+Tau+Glu, NAA and Tau (Supplementary Table 2) for mice from the blinded experiment (0 to 9 hours) and compares them with the actual permanent MCAO times, real PIO, Table 1. The gene discussed is MAPT; the disease is ischemia.