HAVCR2 and HIV-1 infection: As shown in figure 2, significantly higher HAVCR2 expression was observed following in vitro HIV-1 infection in AG heterozygotes compared to AA homozygotes (Student's t-test, p = 0.028) (Fig. 2); the same trend was observed in uninfected PBMCs, although the difference was less marked and did not reach statistical significance (Fig. 2).