miR-328 expression was found to be elevated in blast crisis chronic myelogenous leukemia (CML-BC) via the MAPK pathway, causing differentiation, impairing leukemic blasts survival through acting as a sponge molecule, decoying away hnRNP E2, a repressive protein, from C/EBPα, and eventually leading to C/EBPα expression upregulation [131]. This evidence concerns the gene CEBPA and chronic myelogenous leukemia, BCR-ABL1 positive.