These hallmarks of cancer in cervical cancer cells have now all been shown to be driven by HPV oncogenes via the induction of potent proinflammatory pathways—in particular, by inducing expression of the immediate early oncogene COX-2 and expression of the E-series prostaglandin receptors (PTGER) such as PTGER2 and PTGER4 [14–16]. Here, PTGER2 is linked to cervical carcinoma.