In order to verify if P2Y12 recognized by c-ter antibody exclusively in microglia from rat brain slices could be used as specific microglia marker during neuroinflammation, we validated its use in a typical neuroinflammatory disease such as ALS and for the first time characterized the presence of P2Y12 receptor in SOD1-G93A mouse model (Figure 4). Here, SOD1 is linked to amyotrophic lateral sclerosis.