SOD1 and amyotrophic lateral sclerosis: To test if c-ter antibody can further recognize microglia activation during the progression of ALS, we next examined SOD1-G93A spinal cord sections at two different stages of the disease, that is, 20 weeks, a phase when the disease accelerates, and end stage, that is, 23 weeks, when the animals reach the score of 1 accordingly to a behavioral score system [22].