PCDHAC2 and kidney neoplasm: Previous studies described the suppression of promoter DNA methylation, which locates the region 3′ proximal to the Pcdh-α cluster (Pcdh-α12, Pcdh-αc1 and Pcdh-αc2 in wild-type mouse brain and PCDHA13, PCDHAC1, and PCDHAC2 in normal human kidney and human kidney tumor)34, 36, 38.