The results showed that IgGγ expressions of tumor tissues from group 3 (IGHG1 shRNA) or 4 (IGHG1 shRNA with LPS treatment) were lower than that from group 1 (Control shRNA) or 2 (Control shRNA with LPS treatment) at both protein and mRNA levels (Fig. 8A). Here, IGHG1 is linked to neoplasm.