Nevertheless, the conversion of rBCV to aBCV at a later stage of infection, i.e. 48 h and 72 h p.i., seems to be dependent on ULK-1, Beclin1, Atg14L and hVps34 but independent on Atg5, Atg7, Atg16L1 and Atg4B [12]. This evidence concerns the gene ATG5 and infection.