CCR7 and asthma: For the mice sensitized with OVA and transplanted with rAdV-CCR7- and rAdV-TCLA4Ig-infected DCs before OVA challenge, all asthma symptoms, including dysphoria or asthenia, nodding with breathing, forelimb shrinkage and gatism were improved greatly, and the respiratory rate decreased to 120 ± 19 beats per minute, which is similar to the normal control (Table 3).