NYHA class, NT-pro-BNP, TNF-alpha, sFAS/sFAS ligand ratio, and LVEF remained statistically significant for all the categories; i.e., all-cause mortality, CHF-related death, and CHF-related rehospitalizations, whereas type two diabetes mellitus and three- and multi-vessel lesion did not. The gene discussed is NPPB; the disease is congestive heart failure.