FTO and early-onset autosomal dominant Alzheimer disease: Prior studies have suggested several other phenotypes that may be associated with FTO variants, including pancreatic cancer, Alzheimer's disease, attention deficit hyperactivity disorder, and alcoholism (Keller et al., 2011; Lurie et al., 2011; Sobczyk-Kopciol et al., 2011; arcOGEN Consortium et al., 2012; Corella et al., 2012; Reitz et al., 2012; Velders et al., 2012).