Huang et al. also found no correlation between VCAM-1 and FIGO stage in OC patients in their study but they examined the expression of VCAM-1 in ovarian cancer tissue samples and not in human fluids.21 A possible explanation could be that sVCAM-1 in the two fluids does not reflect the stabilized spread of the disease defined by stage but by the biologic potential of ovarian cancer to metastasis. This evidence concerns the gene VCAM1 and ovarian cancer.