Genes drastically up-regulated by OM fungi were included in subcluster 8, the functions of these genes were related to signaling (serine/threonine protein kinase), reactive oxygen species homeostasis and stress-related (GST, lectin, pathogenesis-related protein 10–3.2), protein metabolism and processing (ribosomal protein L10e, subtilisin, serine carboxypeptidase 1, elongation factor, amino-peptidase) and transport (ABCG, oligopeptide transporter OPT family). This evidence concerns the gene CPQ and ocular melanoma.