Risk of T-cell NHL was higher with concomitant use of TNF-alpha inhibitor with thiopurines (95% CI 4.98-354.09; P < 0.0001) and thiopurines alone (95% CI 8.32-945.38; P < 0.0001) but not with TNF-alpha inhibitor use alone (95% CI 0.13-10.61; P = 1.00) [34]. This evidence concerns the gene TNF and T-cell non-Hodgkin lymphoma.