N-myc interactor (NMI) is a cytokine (IL-2, IFNγ) inducible protein that interacts with several transcription factors such as STATs, cMYC, BRCA1, TIP60 and SOX10, all of which have known critical involvement in influencing tumor progression and stem-ness [1–6]. The gene discussed is NMI; the disease is neoplasm.