Interestingly, α-enolase interacts with different viral proteins during the infection, including the capsid protein from DENV, envelope protein from WNV, NS3 protein from Kunjin virus (a variant of WNV) and NS5 protein from Tick-borne encephalitis virus and from Alkhurma virus [42]–[43], although the biological relevance of these interactions remains unclear. This evidence concerns the gene RAF1 and infection.