PNPLA3 and steatosis: There was no statistically significant difference in the prevalence of grade 2–3 steatosis according to PNPLA3 148M/M status (p = ns), although a nonsignificant trend was observed in the whole cohort including subjects with ultrasonographic estimation of steatosis severity (7/21, 33% vs. 44/226, 19% in 148M/M vs. individuals carrying other PNPLA3 genotypes, p = 0.15).