TGFB1 and cancer: Many of the molecular pathways identified by the miRPath tool in irradiated mice fed a normal diet were known to be associated with radiation responses and/or cancer, such as the TGF-β [93], MAPK [94], ErbB [95] and Wnt [53] signaling pathways, apoptosis, etc. Interestingly, these radiation-induced miRNA regulations were not observed in irradiated obese mice.