For example, we see the following major clusters: a hematopoietic cluster (red), which contains sub-clusters that include PBMCs, AML samples, B-ALL samples, and the CD45+ immune cell fraction of primary ccRCC samples; an epithelial cancer cell line cluster (green) composed of multiple sub-clusters; a fibroblast cluster (orange) which includes CAFs derived from SOC and HNC and normal dermal fibroblasts; and a ccRCC cluster (blue), which contains both early passage in-house cell lines and primary samples. This evidence concerns the gene PTPRC and nonpapillary renal cell carcinoma.