HTR1B and permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome: Given the potential involvement of 5-HT-1 receptors signaling to the proliferation of several types of cancers, with unknown implications of these receptors on PaCa progression, we investigated here the role of 5-HT1B and 5-HT1D receptors in the proliferation and the invasive phenotype of PaCa.