AFP and metastatic neoplasm: If based on radiological images and AFP levels alone, atypical hemangiomas with diameters less than 3 cm, metastatic tumors with necrosis, cystic degeneration or rich blood supply, inflammatory pseudotumors of the liver, and focal nodular hyperplasias, may lead to a false diagnosis, causing unneccessary surgical resection, liver transplantation, or other inappropriate treatments.