Although data for this staining were limited as only ex vivo cultures from 3 patients with Reflux Esophagitis were measured, significantly lower numbers of CD4+CD103+-cells were found in ex vivo cultures of RE when compared to normal looking proximal esophageal epithelium of BE patients (RE vs BE SQ 5 cm, p = 0.02) (Figure 3). The gene discussed is CD4; the disease is gastroesophageal reflux disease.