In normal looking proximal squamous esophageal epithelium very low percentages of CD103−cells inside CD8+GranzymeB+-population (CD8+GranzymeB+CD103−) were found (0.6±0.3% in BE SQ and 1.6±0.3% in C SQ 5 cm) (Figure 6, panel A). The gene discussed is CD8A; the disease is Barrett esophagus.