Other 4 carbon structures (i.e. GABA or γ-OH butyrate – which is accumulated as a result of succinic semialdehyde dehydrogenase deficiency, a rare autosomal recessive disorder which presents with autistic behaviors, [100]) and following ketogenic diet administration, a possible therapy for ASD, also have potent effects on CNS function via the dopaminergic system suggesting a broader implication of this putative mechanism. Here, ALDH5A1 is linked to hyperinsulinemic hypoglycemia, familial, 4.