IGF1R and neoplasm: (Figure 1) M1 demonstrated the greatest response to therapies SCH 717454 and BMS 754807, with near complete regression of tumors in response to antibody SCH 717454 (mean tumor volume in anti-IGF1R antibody arm vs placebo arm at 5 weeks, 1.09 cm3 vs. 0.04 cm3, p<0.001).