Genes perturbed by 3 of 59 transcription factors in knock-down experiments (Cusanovich et al., 2014) were enriched for association with T1D (Fig. 4): IKZF3 (P = 1.1 × 10−4,n=1798), BATF (P = 4.4 × 10−4,n=210) and ESRRA (P = 8.0 × 10−4,n=614), where n is the number of genes in each set. The gene discussed is IKZF3; the disease is type 1 diabetes mellitus.