Recent in vitro functional data demonstrated that the T-allele was protective against breast cancer mortality by first increasing mature hsa-mir-202 expression levels, leading to subsequent down-regulation of its gene targets, including cancer related genes CRYBB2, DICER1, SART1, S100A8, P2RX3, and BRCA1[42]. The gene discussed is SART1; the disease is breast carcinoma.