Not surprisingly, GzB is expressed in a number of T/NK cell neoplasms including anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) [8–11], ALK- ALCL [8–10], and nasal-type NK/T cell lymphoma [10, 12], as well as other lymphoid cancers including some Hodgkin lymphoma [13–15] and multiple myeloma [16]. Here, ALK is linked to anaplastic large cell lymphoma.