This led us to conclude there is a cell type difference in Nxf1-mediated NP mRNA nuclear export: in human lung adenocarcinoma epithelial cell line (A549) NP mRNA nuclear export is Nxf1-mediated while in human embryonic kidney cell line (293 T) NP mRNA nuclear export is Nxf1 independent. This evidence concerns the gene NXF1 and lung adenocarcinoma.