For instance, the sentences ‘Nowadays, alpha fetoprotein is the most widely used tumor marker for screening and diagnosis of hepatocellular carcinoma.’ and ‘Annexin A2 was then selected for further verification.’ were deemed by all curators to be ‘Relevant’ and ‘Irrelevant’ in relation to the genes ‘AFP’ and ‘ANXA2’, respectively. This evidence concerns the gene ANXA2 and hepatocellular carcinoma.