NFKB1 and rheumatoid arthritis: We next observed that core biological modules, as defined using pathway analysis, designated lymphoid (B cell- and plasmablast-dominated), myeloid (macrophage and NF-κB process dominated) and fibroid (comprising hyperplastic but pauci-immune tissues) could be surveyed across multiple RA patient synovial tissue cohorts to identify reproducible RA phenotypes.