However, on multivariable ordinal regression analysis, CVD was not significantly associated with CKD staging, whereas PEDF remained significantly associated with CKD stages (adjusted P < .001), together with age (P < .001) and microalbuminuria/albuminuria (P = .014), suggesting the association of PEDF with CKD staging to be independent of that between PEDF and CVD. Here, SERPINF1 is linked to chronic kidney disease.