TNS3 and breast carcinoma: Since the specific binding of TPP to Hsp70 could be shown using the ELISA (Fig. 3) and the flow cytometry analysis of tumor cell lines (Fig. 1), the dependency of peptide binding is dependent on the Hsp70 membrane expression of cells, the internalization of peptide into tumor cells was assessed using a panel of breast cancer cell lines which exhibit differences in their Hsp70 membrane expression profiles.